The FDA states that Livalo has the following half-life information: Peak plasma accumulation: 1 hour after initial dosage. High cholesterol Livalo (pitavastatin) dosage forms tablet 1mg 2mg 4mg. Livalo is also used to treat an inherited form of high cholesterol in children at least 8 years old. Statins are cholesterol-lowering medications that help to lower "bad" cholesterol (called LDL) by blocking cholesterol production in the liver. Sequestrants (bile acid-binding resins) are drugs that block the bloodstream from absorbing cholesterol by binding bile to the intestines. Further, it is more than 99% bound to the proteins in plasma; this feature allows for the body to fully transmit the drug throughout. Livalo is a brand name of pitavastatin, approved by the FDA in the following formulation(s): LIVALO (pitavastatin calcium - tablet;oral) Manufacturer: KOWA CO Approval date: August 3, 2009 Strength(s): EQ 1MG BASE , EQ 2MG BASE , EQ 4MG BASE. Livalo has less drug-drug interaction than atorvastatin and simvastatin, as Livalo is minimally metabolized by cytochrome P450 (CYP) enzyme Generic Livalo Availability. Lowering your cholesterol may help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease. Pitavastatin works by blocking an enzyme, called HMG-CoA reductase, in the liver that catalyzes the conversion of HMG-CoA to mevalonate, a rate-limiting step in the synthesis of cholesterol Livalo (pitavastatin) is a statin. In clinical trials: LIVALO reduced LDL (bad) cholesterol up to a mean of 45% at the 4-mg dose. LIVALO, along with a heart-healthy diet and regular exercise, may help improve overall cholesterol levels. Notably, these medications are the oldest drug available that has been used to treat high cholesterol levels Review pharmacology about PITAVASTATIN (LIVALO): Side effects, uses, dosage (2 mg), warnings, precautions, benefits, indications, mechanism of action (MOA). Statins can also raise "good" cholesterol (called HDL). Livalo is a brand (trade) name for pitavastatin (also called pitavastatin calcium) which may be used for the treatment of high cholesterol. What is Livalo (pitavastatin) used for? Livalo is used to treat high cholesterol in adults. Livalo is a brand-name prescription drug. It’s FDA-approved to treat certain forms of high cholesterol when used in combination with a low-cholesterol diet. Livalo reduces levels of total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C) and triglycerides (TG) to a similar level as the most potent statins, simvastatin and atorvastatin. Mean plasma elimination half-life: 12 hours. LIVALO ® (pitavastatin) belongs to a class of medications called statins. Specifically, Livalo is used to treat:. Livalo has an oral bioavailability of 51%.
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